Welcome to the OpenFold Consortium

• Employees
  • Jennifer Wei, Ph. D. – Leading the development of the OpenFold models and infrastructure.
  • Mallory R. Tollefson, Ph.D. – Business Development and Project Manager, coordinating technical projects and community initiatives across OpenFold and OpenADMET.
• Executive Committee (EC) – An elected subset of our governing board, representing industry perspectives, which guides strategy and ensures that OpenFold remains community-focused. Current bylaws limit this board to six members. Current members include:
  • Peter Clark, Ph.D. – Vice President, Computational Drug Design, Novo Nordisk
  • Lucas Nivon, Ph.D. – CEO & Co-Founder, Cyrus Biotechnology
  • Woody Sherman, Ph.D. – Chief Innovation Officer, Psivant Therapeutics
  • Christina Taylor, Ph.D. – Senior Science Fellow & Computational Molecular Design Lead, Bayer Crop Science
  • Brian Weitzner, Ph.D. – Director of Computational & Structural Biology, Outpace Bio
  • Alexandre Zanghellini, Ph.D. – Co-Founder & CEO, Arzeda
• Technical Advisory Council (TAC) – An elected subset of our governing board who provide scientific and technical expertise on research directions and model development. Current bylaws do not limit the size of the TAC. 
• Governing Board (GB) – Any representatives from our signed member companies (unlimited seats), with each company getting a vote (limited) that is proportional to the member company’s membership tier.
• Supporters – Community members from academia or industry who support our efforts through donated expertise.

• Mohammed AlQuraishi, Ph. D. – Professor at Columbia University leading the scientific development of OpenFold.
• Gabriel Rocklin, Ph.D. – Professor at Northwestern University developing methods for large-scale wet lab measurements of thermodynamic folding stability.

• Slack – The primary hub for daily discussions, with private channels available for focused collaborations. Please contact mallory.tollefson@omsf.io to join our Slack workspace.
• Email Addresses:
  • support@openfold.io – you can use this email list to reach technical support while using our software.
  • info@openfold.io – this email address is for public inquiries.
  • openfold-news@openfold.io – this email group is open to the public and is for anyone who enjoys quarterly OpenFold updates! Reach out to Mallory (email above) if you would like to join.
  • executive-committee@openfold.io – this email reaches all 6 members of our Executive Committee and can be used to communicate about comments on the directions of the consortium or other governing needs.
  • technical-advisory-council@openfold.io – this email group reaches members of the TAC and can be used to log technical ideas or problems that should be discussed at a TAC meeting.
  • openfold-members@openfold.io – this email will reach all 170+ governing board members; please only use this email for announcements relevant to all governing board members.
  • mallory.tollefson@omsf.io – contact Mallory to get more involved in the consortium.
  • aq-lab@openfold.io – you can use this email list to reach AlQuraishi and trainees at Columbia who develop our software for technical assistance.

We do not currently have any subgroups, but if you are interested in leading a subgroup on any topic, please reach out to mallory.tollefson@omsf.io. Potential subgroups below.

• Antibody/antigen modeling
• Protein Design
• Generative small molecule design
• Fine-tuning on internal data

Consortium members have early access to OpenFold3, our newest all-atom foundation model until our public release

What’s included in the current beta release:

• A new set of checkpoint weights (main-stage training complete; fine-tuning in progress).
• Template support for inference.
• Docker images, documentation, and development-branch code access.

To access:

• Submit your GitHub ID to mallory.tollefson@omsf.io for repository permissions.
• Use the provided Docker images and docs for setup (email mallory.tollefson@omsf.io if you have lost access)

Share feedback via our feedback form rather than GitHub issues until the public release.

Your feedback, collaboration, and engagement are what make the OpenFold Consortium thrive. We encourage you to stay active on Slack, respond to our community survey, and join in discussions that will shape the future of OpenFold.

Thank you for being part of this growing community!